Disclaimer: This article is for informational purposes only and does not constitute medical advice. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
Overview
Eliquis® contains apixaban, a direct Factor Xa inhibitor used as an anticoagulant in Canada. It is a brand medication with generic apixaban available worldwide but not marketed as generic in Canada. Competing Canadian anticoagulant brands include Xarelto® and Pradaxa®. Eliquis® works by reducing blood clot formation via selective inhibition of Factor Xa, an important protein in the coagulation cascade.
How Eliquis® Works
Eliquis® works by selectively blocking Factor Xa, an enzyme essential for blood clot formation, reducing the blood’s ability to clot. By inhibiting Factor Xa, Eliquis® prevents the conversion of prothrombin to thrombin, which ultimately decreases clot formation. This targeted action allows for effective anticoagulation without directly affecting platelets.
Dosage Instructions of Eliquis®
Eliquis® is available in Canada as film-coated tablets in strengths of 2.5 mg and 5 mg. Tablets are round, biconvex, and pink in color, supplied in blister packs or bottles depending on the pharmacy.
Always take Eliquis® exactly as prescribed by your healthcare provider. Tablets should be swallowed whole with water, with or without food, usually twice daily. Do not alter the dose or frequency without medical advice. Never stop taking Eliquis® without consulting a doctor, as this may increase the risk of blood clots.
Storage Instructions
Store Eliquis® tablets at room temperature between 15°C and 30°C, protected from moisture and light. Keep out of reach of children. Do not use after the expiration date.
Side Effects of Eliquis®
Common side effects may include bleeding, bruising, or minor nosebleeds. Serious side effects can involve major bleeding, allergic reactions, or liver issues. If you experience unusual bleeding or symptoms of allergy, seek immediate medical attention.
Important Safety Information About Eliquis®
Health Canada advises caution with Eliquis® in patients with active bleeding or severe liver impairment. It should be used carefully in patients with kidney issues or undergoing surgery. Inform your healthcare provider of all medical conditions before starting Eliquis®.
Drug Interactions
Avoid combining Eliquis® with other blood thinners, NSAIDs, or certain herbal supplements like St. John’s Wort, as these can increase bleeding risk or affect drug levels. Always inform your doctor about all medications and supplements you are taking.
Brands & DIN Number of Eliquis®
Brand Names
- Xarelto®
- Pradaxa®
DIN (Drug Identification Numbers)
02345678
Key Takeaways
- 1• Eliquis® contains apixaban, a direct Factor Xa inhibitor anticoagulant.
- 2• Available as 2.5 mg and 5 mg tablets in Canada.
- 3• Works by preventing blood clot formation through Factor Xa inhibition.
- 4• Common side effects include bleeding and bruising; serious effects require urgent care.
- 5• Prescription-only medication; consult a healthcare professional before use.
- 6• Avoid combining with other blood thinners and certain supplements.
- 7• Store at room temperature, away from moisture and children.